A Review on Biomedical Applications of PolymericNanoparticles by A Krishna Sailaja in DDIPIJ in Lupine Publishers.
Splendid achievements have been made in management of disease through
invention of drugs over past decade. The present
conventional drug delivery systems often have side-effects and
complications due to their wide distribution throughout the body
fluids. The localization of drug action in injured tissue is a promising
way to solve this problem. The objective of drug targeting is
to achieve a desired pharmacological response at a selected site without
undesirable interaction at other sites. This is especially
important in cancer chemotherapy and rheumatoid arthritis treatment.
Recently invention of drugs has been generated by
various drug delivery systems like microspheres, liposomes, noisomes,
nanocapsules and nanoparticles. Among all colloidal drug
carriers’ nanoparticles are gaining more popularity because of their
stability, easy preparation, for achieving reduced toxicity, for
increased drug efficacy & site targeted action. Nanoparticulation is
a very useful strategy towards targeted drug delivery and also
for enhancement of bioavailability of low soluble drugs. In this article
nanoparticles preparation methods and their biomedical
applications were discussed in detail.
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